Director, Translational Sciences Job at Work In Biotech, Seattle, WA

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  • Work In Biotech
  • Seattle, WA

Job Description

About InduPro
InduPro, Inc. is bringing life-changing therapies to patients through novel cell-surface platform technologies. We are defining and manipulating protein interactions beyond natural signaling paradigms. InduPro platforms integrate inherent protein proximity at the cell surface with the ability to manipulate protein pairings via induced protein proximity to create novel signaling pathways and logic gates. Our culture fosters innovation at every level.



The Opportunity


InduPro is seeking a highly motivated scientific leader to support pre-clinical and clinical translational activities across our emerging pipeline. This individual will play a key role in developing and deploying the translational strategy for discovery and early development stage programs covering both oncology and autoimmune disorders. Experience in overseeing IND enabling activities and developing biomarkers for clinical trials is required.
Responsibilities Include

  • Design, plan and provide oversight of pre-clinical IND enabling studies, as well as PK/PD analysis, interpretation, and reporting of results for therapeutic candidates (bi-specific antibodies/ADCs) in early development
  • Support scientific input and review of all translational medicine aspects of regulatory documents, including but not limited to development plans, study reports, study protocols, regulatory submissions and responses to regulatory questions
  • Formulate translational strategies for the discovery, development, and implementation of biomarkers that assess proof of mechanism, establish early signs of efficacy, enable proof of concept studies, patient selection and generate an understanding of the variability in patient response
  • Effectively collaborate cross-site and cross-functionally (e.g., research, biologics, in vivo pharmacology,) to ensure successful operational execution of translational plans
  • Communicate data and strategies effectively to key stakeholders, including internal team members, senior management, and external partners

Requirements & Qualifications

  • Ph.D. in molecular biology, biochemistry or relevant scientific field with a well-documented background of scientific achievement, and 7+ years of biotech/ pharmaceutical drug discovery and development experience
  • Experience in design and oversight of IND enabling pre-clinical studies for bi-specific antibodies/ADCs strongly preferred
  • Experience with identification and validation of pharmacodynamic and patient selection biomarkers and clinical implementation
  • Understanding of clinical trials and clinical strategy, experience with bi-specific antibody/ADC drug development as well as analytical and clinical validation of biomarker assays
  • Familiarity with PK, PK/PD modeling and analyses
  • Ability to drive and influence projects from discovery through early clinical development with a focus on the identification of indications with biomarkers of response and/or resistance to therapy
  • Strong strategic and critical thinking skills, with a demonstrated ability to analyze, interpret, and clearly communicate (written and oral) complex data and its impact on program and regulatory strategy
  • Excellent leadership and communication skills, with the ability to collaborate effectively in a team-oriented environment
  • Proven track record of successfully mentoring and developing the careers of direct reports
$200,000 - $240,000 a year
The anticipated salary range for this position is $200,000 to $240,000. The final salary will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc.


On top of base salary, we offer comprehensive benefits, bonus, and equity. If this range doesn't match your expectations, please still apply because we may have another opportunity for you.



Benefits
At InduPro we believe that being face to face helps enhance collaboration, innovation, productivity, employee well-being, employee engagement, and Company culture.


Every member of the InduPro team plays a role in shaping our science and our culture in a dynamic startup environment. We offer a competitive total compensation package, including stock options, participation in an annual performance bonus incentive program, a comprehensive benefits package, paid time off, and exciting opportunities for professional development.


Benefits include medical, dental, and vision coverage; company-paid life and disability insurance; supplemental life and disability insurance; voluntary accident, critical illness, and hospital indemnity insurance; a 401(k) plan with employer matching contributions; flexible spending accounts; an employee assistance program; flexible paid time off; 10 paid company holidays; and employee access to voluntary auto, home, legal, and pet insurance.


InduPro, Inc. is an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability, or any other status protected by federal, state, or local law.

Job Tags

Holiday work, Local area, Flexible hours,

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