Job Description
Why Work With Us?
At Candel, our people drive our success. We value diversity, collaboration, and bold thinking in a supportive, mission-driven environment. We are a high performing team; we show up for each other and stay focused on making a difference for patients and families. Our leadership is transparent and empowering, and our culture is built on trust, flexibility, and accountability, encouraging ownership and innovation every day.
Our Science: Advancing Cancer Immunotherapies
Candel is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses. Our platforms use genetically modified adenovirus and HSV constructs. With positive Phase 3 results for our lead candidate, it’s an exciting time to join us and help bring transformative cancer treatments to patients. Learn more:
Position Summary:
If you’re a hands-on, detail-driven clinical research professional who thrives on collaboration and purpose, this
role puts you at the heart of Candel Therapeutics’ mission to advance oncology research. As a
Senior Clinical Research Associate (CRA) , you’ll serve as the key link between clinical sites and the Candel team—ensuring that every study runs with precision, integrity, and compassion for the patients at its core.
You’ll play a vital role across multiple oncology programs, overseeing site readiness, patient recruitment, on-site and remote monitoring, and study close-out. Your proactive mindset and ability to think both strategically and tactically will help ensure studies stay compliant, on schedule, and data-driven—while fostering positive, trust-based relationships with investigators and coordinators.
NOTE: This is a work from home office role with travel up to 80% (3-4 days every week)
What You’ll Do:
- Be the bridge between sites and Candel. Act as the primary liaison for all site communications ensuring alignment, transparency, and timely updates between investigators, study staff, and internal teams.
- Lead site operations end-to-end. Conduct pre-study assessments, initiation visits, on-site and remote monitoring, and study close-outs in full compliance with GCP, SOPs, and FDA regulations.
- Champion quality and compliance. Verify that data are accurate, complete, and protocol-adherent; ensure all essential documents and training records are current and audit-ready.
- Drive patient recruitment and retention. Collaborate with sites to develop tailored recruitment strategies and maintain strong participant engagement.
- Monitor data flow and timelines. Track data entry, query resolution, biospecimen and bioimaging submissions, and safety reporting—proactively resolving issues before they impact deliverables.
- Partner with CTMs for continuous improvement. Support CAPA implementation for QA findings and contribute insights that strengthen future study execution.
- Manage site-level operations. Oversee cost tracking, coordinate payments, and maintain accurate documentation throughout the study lifecycle.
- Collaborate cross-functionally. Work with internal stakeholders to refine study tools, SOPs, and Case Report Forms (CRFs), helping shape best practices that raise the bar for operational excellence.
What You Bring
- Bachelor’s degree required; Master’s preferred in a health-related discipline.
- 3+ years of experience in oncology clinical trials with strong command of GCP, FDA regulations, and industry best practices. (This is a "must have".)
- Proven ability to manage multiple studies and databases independently while maintaining high standards of accuracy and efficiency.
- Excellent communication, organizational, and relationship-building skills—able to influence without authority and navigate complex site dynamics.
- Strong technical proficiency with Microsoft Office and familiarity with common project management tools.
- Sound judgment, professionalism, and discretion when handling sensitive or confidential information.
Why You’ll Succeed at Candel:
- You know how to get things done without needing step-by-step instructions.
- You value collaboration over ego and strive to lift others as you grow.
- You’re excited to join a growing company and make a tangible impact.
- You care about patients, science, and people—in that order .
Work Environment:
This remote role will be based in East coast or mid-west locations preferably for convenience of time zones.
Job Tags
Full time, Work at office, Work from home, Home office, 3 days per week,